British Air Force Typhoon FGR4s have operated alongside French aircraft in a joint strike targeting an hidden munitions depot in Syrian territory employed by the Islamic State group (IS), per a report from the UK Ministry of Defence.
The location, located using intelligence, was thought to be storing arms and explosives, the statement said, and was located in hills just to the north of Palmyra in Syria's central region.
"The RAF jets used laser-guided Paveway IV weapons to strike a several approach shafts leading to the depot... early reports indicate the strike was effective," the MoD said.
There was no sign of any civilian impact in the strike late on Saturday and every plane involved returned safely, the defence officials confirmed.
The Typhoon fighters were backed up by a Voyager tanker plane.
The Islamic State group - referred to as the so-called Islamic State - established militant control over significant areas in both Syria and Iraq prior to its 2019 collapse.
"This operation shows British leadership, and determination to work closely with allied nations, to stamp out any revival of Daesh and their dangerous and violent ideologies in the area," the British Defence Secretary the Defence Secretary remarked.
UK warplanes have carried out patrols over Syrian airspace to "prevent any attempted comeback" of IS following its military defeat at the Baghuz confrontation in 2019, the ministry said.
"I must thank all the members of British forces involved in this operation for their skill and their courage," the Defence Secretary commented. "They were among thousands of UK service members stationed over the festive period. This operation, to eliminate militants who endanger our security, highlights how our armed forces are always on standby, all year round, keeping Britain secure at home and powerful internationally."
Last December, the United States armed forces carried out what it termed a "large-scale strike" against Daesh sites in the country, after an attack resulted in the deaths of two US servicemembers and a civilian linguist in the Palmyra area.
The United Nations estimates Islamic State still boasts an estimated 5,000 to 7,000 militants in both countries.